Xanthelasma Palpebrarum and Corneal Arcus in Octogenarians

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Abstract
To the Editor: Xanthelasma palpebrarum and corneal arcus, especially in the young, have been associated with dyslipoproteinemia and an increased risk of coronary artery disease.1 , 3 Few reports, however, have described these lipid deposits in older subjects. We have studied the prevalence of xanthelasma and corneal arcus in 236 unrelated and relatively healthy octogenarians (118 men and 118 women) with a mean age of 84.7±4.24 years (range, 80 to 100), selected for a study of apolipoprotein E phenotypes that was designed to relate allele frequency to coronary artery disease. The criteria for entry were autonomy, ability to ambulate, and absence of . . .