Short term screening tests for carcinogens
- 1 May 1976
- journal article
- review article
- Published by Springer Nature in Nature
- Vol. 261 (5557) , 195-200
- https://doi.org/10.1038/261195a0
Abstract
There are now short term tests with a high predictive value for mammalian carcinogens. Many of them are based on the ability to detect damage to DNA in bacteria or mammalian cells after metabolic activation by microsomal enzymes. Their introduction will enable provisional safety assessments to be made for the many thousands of industrial and environmental chemicals for which long-term animal testing cannot be considered.This publication has 61 references indexed in Scilit:
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