Serum factor in fasted rats inhibiting carbohydrate metabolism in the isolated diaphragm
- 1 May 1960
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 198 (5) , 1075-1078
- https://doi.org/10.1152/ajplegacy.1960.198.5.1075
Abstract
A factor has been found in the serum of fasted rats which inhibits glucose uptake and glycogen synthesis in the isolated rat diaphragm. It does not affect CO2 production or O2 uptake. It is nondialyzable, stable in the cold and also stable when heated to 58°C for 1 hour. It was found in Cohn fraction IV-V. Its action did not resemble any of the known hormones, nor could it be identified as one of the inhibitory factors found in diabetic serum.Keywords
This publication has 7 references indexed in Scilit:
- Further Characterization of an Insulin Antagonist in the Serum of Patients in Diabetic AcidosisJournal of Clinical Investigation, 1957
- Glucose Utilization and Lactate Production by Leucocytes of Patients with Diabetes Mellitus.Experimental Biology and Medicine, 1957
- INHIBITION OF MUSCLE GLUCOSE UPTAKE BY DIABETIC RAT SERA OF VARYING GLUCOSE AND LIPOPROTEIN CONTENTJournal of Biological Chemistry, 1957
- STUDIES ON INSULIN ANTAGONISM IN PLASMAEndocrinology, 1957
- ESTIMATION OF PLASMA-INSULIN BY THE RAT DIAPHRAGM METHODThe Lancet, 1954
- INHIBITION OF GLUCOSE UPTAKE BY THE SERUM OF DIABETIC RATSJournal of Biological Chemistry, 1953
- The in vitro synthesis of glycogen in the diaphragms of normal and alloxan-diabetic ratsBiochemical Journal, 1948