Abstract
Eight pediatric patients presenting with acute renal failure (shock kidney, anuria continuing for three to five days) were treated with L-thyroxine (p.o. 5–6 µg per kg per day). Dialysis was not used. Diuresis started within 34 to 46 hours. Serum levels of urea and creatinine normalized within a very short time. The results are discussed on the basis of a new hypothesis concerning the RPF- and GFR-raising action of thyroid hormone in the normal situation and in acute renal failure.