EFFECTS OF POSTERIOR PITUITARY EXTRACTS ON BASAL METABOLISM
- 1 March 1931
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 96 (3) , 640-646
- https://doi.org/10.1152/ajplegacy.1931.96.3.640
Abstract
In 64 experiments on 20 rats the changes in O consumption, CO2 production and R.Q. after the subcutaneous injection of pituitrin, pitressin, and pitocin, were determined by Hal-dane''s method. The decrease of the metabolic rate by pituitrin is due to pitressin and occurs despite the effect of pitocin, since pitressin markedly diminishes the metabolic rate, while pitocin increases it slightly, but definitely. Such opposing actions may explain some of the inconsistencies in the literature since the different preparations used by various observers may have contained varying amounts of the oxytocic and pressor principles. Moreover, some of the previous workers injected pituitrin peripherally in doses too small to produce definite changes, since in the present experiments effects on metabolic rate were observed only with large doses.This publication has 6 references indexed in Scilit:
- The anti-diuretic effect of the separated principles of the pituitary bodyThe Journal of Physiology, 1929
- The action of posterior pituitary pressor extract on the rabbit's vascular systemThe Journal of Physiology, 1929
- STUDIES ON OXYTOCIN AND VASOPRESSIN: PRESSOR ACTION*†Endocrinology, 1929
- Studies in carbohydrate metabolismBiochemical Journal, 1929
- THE ANTIDIURETIC EFFECT OF PITUITARY OXYTOCIC AND PRESSOR PRINCIPLES ON WATER DIURESIS IN MANEndocrinology, 1928
- THE EFFECT OF PITUITRIN ADMINISTRATION UPON CERTAIN PHASES OF CARBOHYDRATE METABOLISMAmerican Journal of Physiology-Legacy Content, 1927