Predictive Testing for Huntingtons Disease with Use of a Linked DNA Marker
- 3 March 1988
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 318 (9) , 535-542
- https://doi.org/10.1056/nejm198803033180903
Abstract
The probability of carrying the gene for Huntington's disease can in many cases be estimated in the children of affected persons by identifying a specific DNA marker that is genetically linked to the gene. We studied 47 persons at 50 percent risk of inheriting Huntington's disease who requested a presymptomatic or prenatal genetic-linkage test between September 1986 and January 1988. The participants were given pre-test counseling and psychological and neurologic evaluations.This publication has 37 references indexed in Scilit:
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