Repression of interferon-γ-induced inducible nitric oxide synthase (iNOS) gene expression in microglia by sodium butyrate is mediated through specific inhibition of ERK signaling pathways
- 8 August 2005
- journal article
- research article
- Published by Elsevier in Journal of Neuroimmunology
- Vol. 168 (1-2) , 56-64
- https://doi.org/10.1016/j.jneuroim.2005.07.003
Abstract
No abstract availableKeywords
This publication has 30 references indexed in Scilit:
- P2X7 nucleotide receptor activation enhances IFNγ‐induced type II nitric oxide synthase activity in BV‐2 microglial cellsJournal of Neurochemistry, 2003
- p38 mitogen-activated protein kinase mediates lipopolysaccharide, not interferon-γ, -induced inducible nitric oxide synthase expression in mouse BV2 microglial cellsNeuroscience Letters, 2002
- Anti‐inflammatory effects of sodium butyrate on human monocytes: potent inhibition of IL‐12 and up‐regulation of IL‐10 productionThe FASEB Journal, 2000
- The inhibitory action of butyrate on lipopolysaccharide-induced nitric oxide production in RAW 264.7 murine macrophage cellsInnate Immunity, 2000
- Interaction of interferon regulatory factor-1 and nuclear factor κB during activation of inducible nitric oxide synthase transcriptionJournal of Molecular Biology, 1999
- Upstream NF-κB Site Is Required for the Maximal Expression of Mouse Inducible Nitric Oxide Synthase Gene in Interferon-γ plus Lipopolysaccharide-Induced RAW 264.7 MacrophagesBiochemical and Biophysical Research Communications, 1997
- Interaction of p59fynwith Interferon-Activated Jak KinasesBiochemical and Biophysical Research Communications, 1997
- Microglia: a sensor for pathological events in the CNSTrends in Neurosciences, 1996
- Interleukin-1 and Tumor Necrosis Factor-α Synergistically Mediate Neurotoxicity: Involvement of Nitric Oxide and of N-Methyl-D-aspartate ReceptorsBrain, Behavior, and Immunity, 1995
- An immortalized cell line expresses properties of activated microglial cellsJournal of Neuroscience Research, 1992