Nasal Mucociliary Clearance in Patients with Upper and Lower Respiratory Diseases

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Abstract
The nasal mucociliary clearance was measured in 71 subjects with nasal allergy (NA) (56 subjects without sinusitis and 15 with sinusitis), 12 subjects with bronchial asthma (BA) (7 without, 5 with) and 7 subjects with aspirin induced asthma (AIA) using a saccharin test. The results were compared with those obtained in a control group of 15 healthy subjects. The saccharin time (ST) values for both NA and BA subjects without sinusitis (16.9 ± 9.9 and 20.1 ± 9.4 min, respectively) did not differ from that of the healthy subjects (16.3 ± 5.3 min). However, ST values in NA and BA subjects with sinusitis (37.6 ± 22.9 and 57.0 ± 6.7 min, respectively) were significantly higher than those of healthy subjects (p

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