Isolierung und Struktur der Antibiotica Phomin und 5‐Dehydrophomin
- 1 January 1970
- journal article
- research article
- Published by Wiley in Helvetica Chimica Acta
- Vol. 53 (4) , 696-724
- https://doi.org/10.1002/hlca.19700530404
Abstract
From cultures of a Phoma species (strain S 298) (Fungi imperfecti) two new antibiotics, phomine (1) and 5‐dehydrophomine (4) have been isolated. Phomine and 5‐dehydrophomine represent a novel type of macrolide antibiotics, the large lactone ring being fused to a highly substituted octahydro‐isoindole system. Both show cytostatic activity.Keywords
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