camR, a negative regulator locus of the cytochrome P-450cam hydroxylase operon
Open Access
- 31 May 1986
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 166 (3) , 1089-1095
- https://doi.org/10.1128/jb.166.3.1089-1095.1986
Abstract
A 4.27-kilobase insert from a HindIII DNA library of Pseudomonas putida carrying the CAM plasmid allowed coordinate expression of genes camD and camC under control of camR, an upstream regulator. The camC gene specifies cytochrome P-450cam, and camD specifies the 5-exo-alcohol dehydrogenase. A 1.38-kilobase deletion from the insert results in the constitutive expression of genes camC and camD; transformation in trans restores the substrate control, indicating that camR is a negative regulator.This publication has 60 references indexed in Scilit:
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