ALTERATION OF THE INSULIN-LIKE GROWTH FACTOR SYSTEM OF MITOGENS IN HYPERPLASTIC BLADDERS OF PARAPLEGIC RATS
- 1 February 1999
- journal article
- Published by Wolters Kluwer Health in Journal of Urology
- Vol. 161 (2) , 699-705
- https://doi.org/10.1016/s0022-5347(01)61998-0
Abstract
Conclusion Our results suggest that following spinal cord injury, overexpression of IGF-I and underexpression of IGFBP 3 and 5 may lead to hyperplasia of the smooth muscle layer of the bladder.Keywords
This publication has 29 references indexed in Scilit:
- Estradiol and Antiestrogens Regulate a Growth Inhibitory Insulin-like Growth Factor Binding Protein 3 Autocrine Loop in Human Breast Cancer CellsJournal of Biological Chemistry, 1996
- Enhancement of Tamoxifen-Induced Suppression of Insulin-Like Growth Factor I Gene Expression and Serum Level by a Somatostatin AnalogueBiochemical and Biophysical Research Communications, 1994
- Role of insulin-like growth factors in embryonic and postnatal growthCell, 1993
- Regulation and biological effect of endogenous insulin-like growth factor binding protein-5 in human osteoblastic cellsJournal of Clinical Endocrinology & Metabolism, 1993
- Insulin‐like growth factor binding protein (IGFBP‐3), an inhibitor of serum growth factors other than IGF‐I and ‐IIJournal of Cellular Physiology, 1992
- Interference of the IGF system as a strategy to inhibit breast cancer growthBreast Cancer Research and Treatment, 1992
- Identification and molecular characterization of insulin-like growth factor binding proteins (IGFBP-1, -2, -3, -4, -5 and -6)Progress in Growth Factor Research, 1991
- Isolation of a novel insulin-like growth factor (IGF) binding protein from human bone: A potential candidate for fixing IGF-II in human boneBiochemical and Biophysical Research Communications, 1991
- Vascular Smooth Muscle Adaptation to Increased LoadAnnual Review of Physiology, 1987
- The development of reflex bladder activity following spinal cord injury in cats and a method to control itNeurourology and Urodynamics, 1982