Mycobacterium avium Complex Infection

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Abstract
Nora from Dr. Merle A. Sande — The issues addressed in this AIDS Commentary are complex ones. Are organisms that constitute the Mycobacterium avium complex (MAC) significant pathogens in the patients infected with HIV? If they are, how should these infections in this population of patients be treated? Dr. Lowell S. Young has done exactly what we hoped our guest commentators would do — he has given his authoritative opinion in an area of AIDS about which there is very little solid data. Dr. Young is a highly visible infectious diseases clinician-scientist who has recently focused his energies on developing new therapies for MAC infections. In this commentary he addresses a number of key questions: What are the implications of isolating MAC organisms from patients with AIDS? What are the best techniques for isolating these organisms? Under what circumstances is treatment of value? What drugs appear to be most effective? Which ones look good for the future?

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