Human Leukocyte Antigen and Antigen Processing Machinery Component Defects in Astrocytic Tumors
Open Access
- 1 December 2005
- journal article
- Published by American Association for Cancer Research (AACR) in Clinical Cancer Research
- Vol. 11 (23) , 8304-8311
- https://doi.org/10.1158/1078-0432.ccr-04-2588
Abstract
Purpose: To determine the frequency of abnormalities in human leukocyte antigen (HLA) and antigen processing machinery (APM) component expression in malignant brain tumors. This information may contribute to our understanding of the immune escape mechanisms used by malignant brain tumors because HLA antigens mediate interactions of tumor cells with the host's immune system.Keywords
This publication has 40 references indexed in Scilit:
- Development and characterization of human constitutive proteasome and immunoproteasome subunit‐specific monoclonal antibodiesTissue Antigens, 2005
- Differential MHC class II component expression in HPV‐positive cervical cancer cells: Implication for immune surveillanceInternational Journal of Cancer, 2005
- Selective monomorphic and polymorphic HLA class I antigenic determinant loss in surgically removed melanoma lesionsTissue Antigens, 2005
- Characterization of antigen processing machinery and Survivin expression in tonsillar squamous cell carcinomaCancer, 2003
- Natural selection of tumor variants in the generation of “tumor escape” phenotypesNature Immunology, 2002
- Epidemiology of brain tumorsCurrent Opinion in Neurology, 2000
- Selective expression of interleukin-10 gene within glioblastoma multiformeBrain Research, 1994
- Antitumor activity against established intracerebral gliomas exhibited by cytotoxic T lymphocytes, but not by lymphokine-activated killer cellsJournal of Neurosurgery, 1992
- Differential Expression of HLA-DR, DQ, and DP Antigens in Primary and Metastatic MelanomaJournal of Investigative Dermatology, 1988
- FINE SPECIFICITY AND IDIOTYPE DIVERSITY OF THE MURINE ANTI-HLA-A2, A28 MONOCLONAL ANTIBODIES CR11–351 AND KS1Transplantation, 1988