THE EFFECT OF ADULT THYMECTOMY ON THE IMMUNOSUPPRESSION OBTAINED BY TREATMENT WITH ANTILYMPHOCYTE SERUM

Publisher Website
Google Scholar
Abstract
The effect of adult thymectomy on the immunosuppressive action of antilymphocyte serum was evaluated. Antilymphocyte serum suppressed the immune rejection of a tumor xenograft growing in the hamster cheek pouch. The degree and duration of this immunosuppression was studied in thymectomized and intact animals. Tumor growth was evaluated by comparing tumor incidence and tumor volume in groups of animals bearing tumor implants. Thymectomy at 28 days of age significantly enhances the immunosuppressive effect of antilymphocyte serum and delays recovery from this suppression.

This publication has 0 references indexed in Scilit: