Gene constellation of live influenza A vaccines
- 1 June 1980
- journal article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 64 (2) , 171-173
- https://doi.org/10.1007/bf01318021
Abstract
The genotypic composition of several H3N2 vaccinal strains made from PR/8/34 and different wild isolates has been determined. The results suggested that specific gene constellations at the level of the 3 largest RNA fragments, coding the 3 “polymerase proteins” are responsible for their consistent attenuation.Keywords
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