EFFECTS OF SOME LIVER EXTRACTS ON CARBOHYDRATE METABOLISM

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Abstract
INTRODUCTION AND REVIEW OF THE LITERATURE The announcement by Minot and Murphy of the successful therapy of pernicious anemia by a liver diet served as a strong stimulus to the preparation and study of liver extracts. Although the primary interest of investigators has been in the effect of various liver extracts on the hemopoietic system and most of the studies have been confined to patients with pernicious anemia, there has been some consideration of the action of such extracts on other organ systems. With the introduction of injectable extracts in particular, animal experiments have been performed and various side actions of liver preparations have been studied. In the course of such studies of the systemic effects of orally and parenterally administered liver extracts, especially the latter, various observers have noted more or less striking effects on the carbohydrate equilibrium of the body. As might be expected with different men using

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