USE OF CORTICOTROPIN THERAPY FOR IDIOPATHIC ACQUIRED HEMOLYTIC ANEMIA

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Abstract
In the recent literature dealing with the treatment of acquired hemolytic anemia, the action of corticotropin and cortisone is inferred to be equally efficacious. In one of the cases reported by Dameshek and Rosenthal1 the patient relapsed when 200 mg. of cortisone, daily, was substituted for corticotropin; resumption of corticotropin therapy was again followed by remission of symptoms. At a later date, the same patient was treated with cortisone with continued beneficial response. In the case of acquired hemolytic anemia reported by Meyers and co-workers2 there appeared to be no appreciable difference between the effects of cortisone and corticotropin when a favorable outcome could be produced by either drug. The case of idiopathic acquired hemolytic anemia to be reported is interesting because adequate doses of cortisone failed to control the hemolytic process, whereas administration of corticotropin produced a sustained remission. A white woman, age 43 years, was admitted

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