Abstract
The efficacy and side effects of budesonide and disodium cromoglycate (DSCG) in seasonal allergic rhinitis were compared. In a double-blind, double-dummy comparative study, 43 patients with seasonal allergic rhinitis were either treated with budesonide (200 .mu.g twice daily) or DSCG (5.2 mg 5 times daily). After a 1 wk run-in period sneezing bouts and total nasal symptoms were significantly different between the treatment groups during the whole treatment period. The scorings for nasal blockage were significantly different during the last 2 wk of treatment. All differences were in favor of budesonide treatment. The patients'' assessment of the treatment favored budesonide (P < 0.02). Side effects were few and mild, but 1 patient from the budesonide group stopped treatment because of headache.