ALLOGENEIC MARROW GRAFTING FOR TREATMENT OF APLASTIC-ANEMIA - FOLLOW-UP ON LONG-TERM SURVIVORS

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  • 1 January 1976
    • journal article
    • research article
    • Vol. 48  (4) , 485-490
Abstract
Eleven of 24 patients with severe aplastic anemia given marrow grafts from HLA-identical siblings between Oct. 1970 and March 1973 are alive with normal marrow function and continued evidence of engraftment 3-5 yr later. Ten were leading normal lives with no immunosuppressive or other drug therapy since day 100 postgrafting. One had chronic graft-vs.-host disease of the skin which is now slowly improving with no therapy. He returned to full-time employment in the summer of 1975. The long-term well-being of almost half of these initial patients emphasized the importance of marrow transplantation for the treatment of severe aplastic anemia.