Circulating concentrations of cardiac proteins in complicated and uncomplicated Plasmodium falciparum malaria
- 13 October 2004
- journal article
- Published by Wiley in Tropical Medicine & International Health
- Vol. 9 (10) , 1099-1103
- https://doi.org/10.1111/j.1365-3156.2004.01303.x
Abstract
In an unmatched case-control study of 63 non-immune European patients with uncomplicated (n = 52) and complicated (n = 11) falciparum malaria, serum levels of N-terminal pro-brain natriuretic peptide (NT-proBNP), heart-type fatty acid-binding protein (H-FABP), myoglobin, troponin T and creatin kinase-muscle brain were compared. Elevated levels of NT-proBNP and H-FABP indicated myocardial impairment in complicated but not in uncomplicated falciparum malaria. The clinical impact of these findings remains to be evaluated. The pathophysiology of cardiac impairment in complicated falciparum malaria warrants further investigation.Keywords
This publication has 20 references indexed in Scilit:
- Prognostic Value of Combination of Cardiac Troponin T and B-Type Natriuretic Peptide after Initiation of Treatment in Patients with Chronic Heart FailureClinical Chemistry, 2003
- Plasma atrial natriuretic peptide and brain natriuretic peptide are increased in septic shock: impact of interleukin-6 and sepsis-associated left ventricular dysfunctionIntensive Care Medicine, 2003
- B-Type Natriuretic Peptides and Ejection Fraction for Prognosis After Myocardial InfarctionCirculation, 2003
- Plasmodium falciparum–Infected Erythrocyte Adhesion Induces Caspase Activation and Apoptosis in Human Endothelial CellsThe Journal of Infectious Diseases, 2003
- Increased Plasma Natriuretic Peptide Levels Reflect Symptom Onset in Aortic StenosisCirculation, 2003
- Serum Ratio of Heart-Type Fatty Acid-Binding Protein to MyoglobinNephron Clinical Practice, 2003
- The Prognostic Value of B-Type Natriuretic Peptide in Patients with Acute Coronary SyndromesNew England Journal of Medicine, 2001
- Skeletal Muscle Involvement in Falciparum Malaria: Biochemical and Ultrastructural StudyClinical Infectious Diseases, 1999
- Myocardial injury in critically ill patients. A frequently unrecognized complicationPublished by American Medical Association (AMA) ,1995
- Acute Pulmonary Edema in falciparum MalariaNew England Journal of Medicine, 1968