FURTHER OBSERVATIONS ON DECREMENT IN NERVE CONDUCTION

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Abstract
In a sciatic-gastrocnemius preparation from the frog, hydrostatic pressure was applied to local regions of the nerve until conduction was blocked, as indicated by the decline in the response of the muscle to stimuli applied to the nerve on the far side of the compressed region. The. survival period of a majority of fibers in a nerve trunk varied with the area compressed, it taking on the average 50% longer to block conduction when pressure acted over a 4 mm. length of nerve than for 8 mm., thus confirming previous work and indicating decremental conduction extending at least 4 mm. into the compressed region.

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