Gigantism Associated with McCune-Albright's Syndrome
- 1 October 1985
- journal article
- case report
- Published by Georg Thieme Verlag KG in Hormone and Metabolic Research
- Vol. 17 (10) , 522-527
- https://doi.org/10.1055/s-2007-1013594
Abstract
The case of a 16 year-old boy with McCune-Albright's syndrome which is rarely accompanied by gigantism was studied endocrinologically. The stimulation of growth hormone (GH) release by hypoglycemia, the decline of elevated GH by hyperglycemia and a little lower somatostatin like immunoreactivity (SLI) may support abnormalities of hypothalamic function, but the existence of pituitary microadenoma cannot be ruled out because of the paradoxical suppression of GH release by oral administration of bromocriptine (CB-154) and L-DOPA and the stimulation of GH release by intravenous administration of TRH.Keywords
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