Increased sister chromatid exchange events in the human late replicating X
- 1 January 1976
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 32 (2) , 199-202
- https://doi.org/10.1007/bf00291504
Abstract
Human female blood cultures were labeled with BrdU for detecting sister chromatid exchanges (SCEs) by the Hoechst 33258 fluorescence technique. Late labeling with 3H-thymidine and autoradiography allowed the identification of the late replicating X. The mean number of SCEs in the cells was 13. The isopycnotic X showed an exchange frequency according to its relative length in the karyotype; in the late replicating X a doubled number of SCE events was observed.This publication has 15 references indexed in Scilit:
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