The Toxicity of Lead Azide

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Abstract
An investigation of Pb azide as an industrial hazard has indicated that the storage and distribution of Pb in the tissues following the ingestion of this compound are, in general, similar to that of other Pb salts. The acute toxic effect of this substance, however, is associated with the azoimide radical rather than with the Pb. Further evidence confirming this was obtained from observations of the effect of administering Na azide intraperit., subcut., and orally in comparison with similar expts. with Pb azide. The minimum lethal dose of Na azide following inj. lies between 35 and 38 mg./kg. of body wt., while up to 150 mg./kg. of body wt. of Pb'' azide could be injected intraperitoneally without causing death. This is equivalent in amt. to 66 mg. of Na azide. The effect of exposure to hydrazoic acid gas by inhalation was detd. at various concs. and was invariably fatal to rats in amts. beyond 1160 p.p.m. when breathed for 1 hr.

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