Simplified Technique to Produce Toxemia in the Rat: Considerations on Cause of Toxemia
- 1 January 1982
- journal article
- Published by Taylor & Francis in Clinical and Experimental Hypertension. Part B: Hypertension in Pregnancy
- Vol. 1 (1) , 93-103
- https://doi.org/10.3109/10641958209037183
Abstract
Under ether anesthesia a silver clip was placed around the abdominal aorta of pregnant rats, thus reducing the uterine blood flow by 35-45%. This resulted in a toxemia-like syndrome comparable to the one previously produced in other animal species. Consideration is given to the hypothesis that, in a similar way, compression of the abdominal aorta by the pregnant uterus in humans produces uterine ischemia leading to toxemia.Keywords
This publication has 2 references indexed in Scilit:
- Aortocaval compression by the uterus in late human pregnancyAmerican Journal of Obstetrics and Gynecology, 1969
- Attempted production of eclampsia-like syndrome in pregnant ratsAmerican Journal of Obstetrics and Gynecology, 1953