Limb sparing surgery for pediatric musculoskeletal tumors
- 8 January 2004
- journal article
- review article
- Published by Wiley in Pediatric Blood & Cancer
- Vol. 42 (4) , 295-310
- https://doi.org/10.1002/pbc.10406
Abstract
There has been an unprecedented improvement in the survival outcome of children with extremity sarcoma as well as a corresponding increase in percentage of limb‐sparing surgeries being performed over the past many decades. This has been, in part, due to the improved imaging modalities, newer surgical techniques, and advences in neoadjuvant chemotherapy. Limb‐sparing surgery for primary bone and soft‐tissue malignancies in children is becoming an acceptable option of surgical treatment in most cases today. This article outlines the demographics, classification, clinical presentation, imaging, and molecular genetics of pediatric mosculoskeletal tumors and discusses the current treatment principles with emphasis on the state‐of‐the‐art surgical management and limb‐sparing techniques for children with extremity sarcoma.Keywords
This publication has 35 references indexed in Scilit:
- Two Primary Osteosarcomas in a Patient With Rothmund-Thomson SyndromePublished by Wolters Kluwer Health ,2000
- MALIGNANT BONE TUMORS OF CHILDHOODPediatric Clinics of North America, 1996
- Pediatric Soft-Tissue SarcomasOrthopedic Clinics of North America, 1996
- Rhabdomyosarcoma and other soft tissue sarcomas of childhoodCurrent Opinion in Oncology, 1995
- The Third Intergroup Rhabdomyosarcoma Study.Journal of Clinical Oncology, 1995
- Limb sparing versus amputation in osteosarcomaAnnals of Oncology, 1992
- Bone sarcomas as second malignant neoplasms following childhood cancerCancer, 1991
- Prognostic indicators in patients with pulmonary metastasesSeminars in Surgical Oncology, 1990
- Staging of intraosseous extent of osteosarcoma: correlation of preoperative CT and MR imaging with pathologic macroslides.Radiology, 1988
- Osteogenic SarcomaJournal of Bone and Joint Surgery, 1967