Severe Anaphylactoid Reaction to Radiographic Contrast Media

Publisher Website
Google Scholar
Abstract
Patients with a history of anaphylactoid reaction to radiographic contrast medium (RCM) are at increased risk for subsequent reaction. To date, 275 of these high-risk patients have been studied with use of prophylactic pretreatment with diphenhydramine hydrochloride or prednisone or both without a single severe anaphylactoid reaction on readministration of RCM. This report describes a patient who received pretreatment as described in the literature but suffered a life-threatening anaphylactoid reaction on readministration of RCM. Premedication does not eliminate the possibility of a fatal reaction on readministration of RCM. (JAMA241:2813-2815, 1979)

This publication has 3 references indexed in Scilit: