Growth Factor-induced Phosphorylation of Sterol Regulatory Element-binding Proteins Inhibits Sumoylation, Thereby Stimulating the Expression of Their Target Genes, Low Density Lipoprotein Uptake, and Lipid Synthesis
Open Access
- 1 May 2008
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 283 (22) , 15224-15231
- https://doi.org/10.1074/jbc.m800910200
Abstract
No abstract availableKeywords
This publication has 28 references indexed in Scilit:
- Elevated level of SUMOylated IRF-1 in tumor cells interferes with IRF-1-mediated apoptosisProceedings of the National Academy of Sciences, 2007
- SUMOylation regulates kainate-receptor-mediated synaptic transmissionNature, 2007
- Interaction between Sterol Regulatory Element-binding Proteins and Liver Receptor Homolog-1 Reciprocally Suppresses Their Transcriptional ActivitiesJournal of Biological Chemistry, 2007
- Protein Sensors for Membrane SterolsCell, 2006
- Platelet-derived Growth Factor Stimulates Membrane Lipid Synthesis Through Activation of Phosphatidylinositol 3-Kinase and Sterol Regulatory Element-binding ProteinsJournal of Biological Chemistry, 2004
- Overproduction of eukaryotic SUMO-1- and SUMO-2-conjugated proteins in Escherichia coliAnalytical Biochemistry, 2004
- The Peroxisome Proliferator-activated Receptor γ Regulates Expression of the Perilipin Gene in AdipocytesJournal of Biological Chemistry, 2004
- Direct Demonstration of Rapid Degradation of Nuclear Sterol Regulatory Element-binding Proteins by the Ubiquitin-Proteasome PathwayJournal of Biological Chemistry, 2001
- Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathwayOncogene, 2000
- MAP Kinases Erk1/2 Phosphorylate Sterol Regulatory Element-binding Protein (SREBP)-1a at Serine 117 in VitroJournal of Biological Chemistry, 2000