The Coronary Slow Flow Phenomenon – A New Coronary Microvascular Disorder
- 1 July 2002
- journal article
- research article
- Published by S. Karger AG in Cardiology
- Vol. 97 (4) , 197-202
- https://doi.org/10.1159/000063121
Abstract
The coronary slow flow phenomenon is an angiographic finding characterized by delayed distal vessel opacification in the absence of significant epicardial coronary disease. Case-control and observational studies of patients with this phenomenon were conducted to determine the associated clinical features and prognosis. Patients with coronary slow flow (n = 47) differed from controls (n = 47), more often being current smokers (32 vs. 9%; p < 0.01) and presenting with rest pain requiring urgent admission (74 vs. 21%; p < 0.001), usually to the coronary care unit (66 vs. 17%; p < 0.01). During a median 21-month follow-up of 64 slow flow patients, 84% had recurrent chest pain. Based upon these findings and those of previous investigators, it is speculated that coronary slow flow is a new disease entity characterized by acute but recurrent perturbations of microvascular function.This publication has 2 references indexed in Scilit:
- CorrespondenceJournal of the American College of Cardiology, 1999
- Slow coronary flow: Clinical and histopathological features in patients with otherwise normal epicardial coronary arteriesCatheterization and Cardiovascular Diagnosis, 1996