Tumor Detection with 1-Aminocyclopentane and 1-Aminocyclobutane C-11-Carboxylic Acid Using Positron Emission Computerized Tomography
- 1 June 1981
- journal article
- research article
- Published by Wolters Kluwer Health in Clinical Nuclear Medicine
- Vol. 6 (6) , 249-252
- https://doi.org/10.1097/00003072-198106000-00004
Abstract
Eight patients with proven or suspected neoplastic lesions were examined with 1-aminocyclobutane C-11-carboxylic acid and 1-aminocyclopentane C-11-carboxylic acid using positron emission computed tomography. The results of this comparative study have shown that both of these unnatural amino acids have a high affinity for malignant tumors. The potential of nonmetabolizable C-11-labeled amino acids as noninvasive indicators of metabolic tumor activity is demonstrated and discussed.Keywords
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