Macrophages Isolated from Chickens Genetically Resistant or Susceptible to Systemic Salmonellosis Show Magnitudinal and Temporal Differential Expression of Cytokines and Chemokines following Salmonella enterica Challenge
- 1 February 2006
- journal article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 74 (2) , 1425-30
- https://doi.org/10.1128/iai.74.2.1425-1430.2006
Abstract
Macrophages from inbred chickens that are resistant to salmonellosis show greater and more rapid expression of proinflammatory chemokines and cytokines, including the key Th1-inducing cytokine interleukin-18, upon Salmonella challenge than those from susceptible birds. This suggests the possibility that salmonellosis resistant-line macrophages signal more effectively and rapidly and are more able to induce protective Th1 adaptive responses.Keywords
This publication has 25 references indexed in Scilit:
- Cytokine and Chemokine Responses Associated with Clearance of a Primary Salmonella enterica Serovar Typhimurium Infection in the Chicken and in Protective Immunity to RechallengeInfection and Immunity, 2005
- Association of twelve candidate gene polymorphisms and response to challenge with Salmonella enteritidis in poultryAnimal Genetics, 2003
- Functional comparison of heterophils isolated from commercial broiler chickensAvian Pathology, 2003
- Salmonella enterica serovar Pullorum requires the Salmonella pathogenicity island 2 type III secretion system for virulence and carriage in the chickenAvian Pathology, 2002
- In vivo and in vitro studies of genetic resistance to systemic salmonellosis in the chicken encoded by the SAL1 locusMicrobes and Infection, 2002
- Candidate genes for resistance to Salmonella enteritidis colonization in chickens as detected in a novel genetic crossVeterinary Immunology and Immunopathology, 2002
- Localization to chicken Chromosome 5 of a novel locus determining salmonellosis resistanceImmunogenetics, 2001
- Differential cytokine expression in avian cells in response to invasion by Salmonella typhimurium, Salmonella enteritidis and Salmonella gallinarum The GenBank accession numbers for the sequences reported in this paper are AI982185 for chicken IL-6 cDNA and AJ250838 for the partial chicken IL-6 genomic sequence, respectively.Microbiology, 2000
- Resistance to Salmonellosis in the Chicken Is Linked toNRAMP1and TNCGenome Research, 1997
- The use of live vaccines in experimental Salmonella gallinarum infection in chickens with observations on their interference effectEpidemiology and Infection, 1956