Fibronectin Levels in Congenital Thrombocytopenia: Schulman's Syndrome

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Abstract
To the Editor: In 1960, Schulman et al.1 described an eight-year-old girl with a lifelong bleeding tendency that was related to the presence of thrombocytopenia. The patient also had bouts of jaundice, anemia, and reticulocytosis. Marrow aspirates contained increased numbers of immature megakaryocytes. The thrombocytopenia did not respond to splenectomy, but it was dramatically corrected by infusion of normal plasma, only to recur unless this therapy was repeated at intervals of two to three weeks. Subsequently, the patient was studied by a number of physicians, since she moved from city to city. In 1965, after a five-month period of thrombocytopenia . . .

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