Papain-induced changes in the knee joints of adult rabbits
- 1 January 1977
- journal article
- research article
- Published by Medical Journals Sweden AB in Acta Orthopaedica
- Vol. 48 (2) , 143-149
- https://doi.org/10.3109/17453677708985125
Abstract
Rapidly progressing joint disease can be produced in the rabbit by intraarticular injection of concentrated papain. With the use of radioactive thymidine it is possible to demonstrate that the cartilage cells recover their ability to divide by mitosis at the same time as degenerative changes appear in the cartilage. Clusters of chondrocytes arise by mitosis of chondrocytes and not by a floating together of cartilage cells.Keywords
This publication has 20 references indexed in Scilit:
- Thermoanalytical and histological study of intra-articular papain-induced degradation and repair of rabbit cartilage. I. Immature animals.Annals of the Rheumatic Diseases, 1974
- Mitosis in Human Osteoarthritic CartilagePublished by Wolters Kluwer Health ,1972
- Instability of the KneeJournal of Bone and Joint Surgery, 1971
- PAPAIN-INDUCED DEGENERATIVE ARTHRITIS OF THE HIP IN RABBITSThe Journal of Bone and Joint Surgery. British volume, 1971
- Intracartilaginous defects in adult sheepVirchows Archiv, 1971
- Changes induced by sustained pressure in the knee joint articular cartilage of adult rabbitsThe Anatomical Record, 1964
- Localization of Tritiated Thymidine in Articular Cartilage of RabbitsJournal of Bone and Joint Surgery, 1963
- Cartilage Changes after Experimental Immobilization of the Knee Joint of the Young RatJournal of Bone and Joint Surgery, 1963
- Sulphate (35SO4) Uptake by Chondrocytes in Relation to Histological Changes in Osteo-Arthritic Human Articular CartilageAnnals of the Rheumatic Diseases, 1960
- Experimental Immobilization and Remobilization of Rat Knee JointsJournal of Bone and Joint Surgery, 1960