HEMORRHAGIC ENCEPHALOPATHY DURING ARSENIC THERAPY FOR ASTHMA

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Abstract
A serious potential danger inherent in the use of potassium arsenite (Fowler's solution) in the treatment of asthma is illustrated in the following case. REPORT OF A CASE A 34-year-old man came to the Mayo Clinic on June 8, 1952, and was hospitalized at once, because he was in critical condition. The patient had had both pneumonia and asthma in 1941 while in the Army. Nonseasonal asthma had recurred each year, usually in association with respiratory infections. There was no family history of allergy; the patient had no other known allergic condition and had shown no allergy to drugs that had been administered for respiratory infections. On April 18, 1952, the patient had begun to take a liquid that contained arsenic prescribed by a physician. He had followed the directions the physician provided to eliminate danger from the arsenic and had even written to the physician for advice when trouble

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