THERAPY OF NEUROSYPHILIS JUDGED BY ARSENIC PENETRATION OF MENINGES
Open Access
- 1 October 1919
- journal article
- other
- Published by American Medical Association (AMA) in Archives of Neurology & Psychiatry
- Vol. 2 (4) , 369-375
- https://doi.org/10.1001/archneurpsyc.1919.02180100002001
Abstract
Of the methods of neurosyphilitic treatment, the more commonly used are the following: (a) Intensive antisyphilitic medication; this consists of arsphenamin given intravenously, mercury and the iodids with such hygienic and supportive treatment as may be indicated for the individual case. In favor of this treatment is its simplicity and its relative freedom from complications. Arsphenamin given intravenously results invariably in arsenic penetration into the spinal fluid according to Benedict,1and in only 30 per cent, of the cases according to Reiger and Solomon.2The clinical results obtained vary widely; some cases are very successful, others less satisfactory, and some types are absolutely resistant to this form of medication. (b) Drainage of the spinal fluid following previous intravenous injection of arsphenamin has been advocated. It is argued that drainage of spinal fluid increases the amount of arsenic in the spinal fluid following the intravenous injection. This method isKeywords
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