Evidence for the facilitated diffusion of glucose into rabbit oviductal fluid

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Abstract
Glucose movement into the oviductal fluid of rabbits was studied in anaesthetized animals. The oviducts were cannulated at each end, and 2 ml 0.9% NaCl at 37.degree. C were recirculated through the lumen for 4 h. D-Glucose appeared linearly in the fluid, reaching an average concentration of 2.6 mM. The rate of D-glucose appearance was 17 times greater than that of L-glucose, infused i.v., suggesting that a component of the D-glucose movement operated by facilitated diffusion. The oviduct was unable to move glucose against an adverse plasma to lumen concentration gradient. The glucose entering the oviductal fluid apparently originates in the plasma and the mucosal portion of the oviduct may be responsible for this sugar transfer.

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