Candida endocarditis treated with a combination of antifungal chemotherapy and aortic valve replacement.
- 1 November 1975
- Vol. 37 (11) , 1191-1194
- https://doi.org/10.1136/hrt.37.11.1191
Abstract
A case of Candida albicans endocarditis is described in which treatment with 5-fluorocytosine was started after aortic valve replacement, but relapse followed discontinuance of treatment. At a second operation the aortic valve was replaced under 5-fluorocytosine cover and treatment was continued with both 5-fluorocytosine and amphotericin-B. No resistance to 5-fluorocytosine developed, and the candida infection was eradicated. The patient is well 22 months after his operation.Keywords
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