The Stability of 5,6-Dihydrofluorouracil in Plasma and the Consequences for Its Analysis

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Abstract
This study shows that 5,6-dihydrofluorouracil kept in plasma at room temperature deteriorates in time. Preservation is gained by low temperature and low pH of plasma samples. Therefore, plasma samples should be buffered and frozen immediately after being obtained, and thawing should proceed to 5 degrees C only.