Prognostic model to predict survival following first-line chemotherapy in patients with metastatic gastric adenocarcinoma

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Abstract
Background: This study was to devise a prognostic model for metastatic gastric cancer patients undergoing first-line chemotherapy. Patients and methods: A retrospective analysis was carried out on 1455 gastric cancer patients, who received first-line chemotherapy from September 1994 to February 2005. Results: At multivariate level, poor prognostic factors were no previous gastrectomy [P = 0.003; relative risk (RR), 1.191; 95% confidence interval (CI) 1.061–1.338], albumin P = 85 U/l (P = P = P = 0.001; RR, 1.460; 95% CI 1.616–1.836), and the presence of ascites (P = Conclusions: This model should facilitate the individual patient risk stratification and thus, more appropriate therapies for each metastatic gastric cancer patient.