PRODUCT FORMATION PATTERNS AND THE PERFORMANCE IMPROVEMENT FOR MULTISTAGE CONTINUOUS STIRRED TANK FERMENTORS

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Abstract
The relationship between the product formation patterns and the performance improvement was studied for the multistage chemostat system. The performance evaluation was made based on the noninferior sets defined for the productivity and the product concentration. It is shown that when the strong product inhibition or the substrate inhibition occurs, the significant improvement can be attained by increasing the number of stages. It is also shown that the maximum product concentration attainable can be increased by increasing the number of stages for the case where either the cell maintenance coefficient or the product decomposition rate is nonzero. If the productivity is the only performance criterion, the performance improvement cannot be attained by increasing the number of stages for the growth-associated type of product formation, while it can be expected for the non-growth-associated type.

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