Orbital Tumor Diagnosis by Positron Emission Tomography Using 18F-Fluorodeoxyuridine
- 1 January 1986
- journal article
- research article
- Published by S. Karger AG in Ophthalmic Research
- Vol. 18 (5) , 292-298
- https://doi.org/10.1159/000265451
Abstract
The distribution of 18F-labeled 5-fluoro-2’-deoxyuridine (18F-FdUrd) in orbital tissue, tumor and aseptic inflammation was examined in rats. The distribution in paraorbital structures, other than bone, was low. The tumor-to-organ ratios were sufficient for tumor imaging by positron emission tomography (PET). Positron emission tomography with 18F-FdUrd clearly showed the experimental orbital VX-2 tumor in rabbits. The difference between the experimental orbital tumor and croton oil-induced aseptic inflammation or a normal orbit was apparently established in the PET image with slow and fast clearance of radioactivity, respectively.Keywords
This publication has 1 reference indexed in Scilit:
- Studies on 18F-labeled pyrimidinesEuropean Journal of Nuclear Medicine and Molecular Imaging, 1984