SCLEREDEMA "ADULTORUMIS" IN CHILDREN
- 1 December 1963
- journal article
- review article
- Published by American Academy of Pediatrics (AAP)
- Vol. 32 (6) , 1044-1054
- https://doi.org/10.1542/peds.32.6.1044
Abstract
The literature on scleredema adultorum of Buschke "acute scleriasis" of Piffard) is reviewed, pointing out the clinical features, course, pathology, and therapy of the disease. Three cases of scleredema adultorum occurring in children are described, and the relatively high frequency of the disease in children is emphasized. Histochemical studies demonstrate a probable accumulation of a mucopolysaccharide into and between the collagen fibers of the dermis. The observations suggest that the material is either chondroitin sulfate A or hyaluronic acid. A basis for the accumulation of the increased amounts of the mucopolysaccharides is considered.Keywords
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