An analysis of the normal ranges of lymphocyte subpopulations in children aged 5–13 years

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Abstract
Peripheral blood lymphocyte subsets were examined in 233 healthy school children aged 4.9–13.7 years at the time of examination. Lymphocyte subsets were characterized according to the following cluster of differentiation (CD) numbers: CD2, CD4, CD8 and CD19 and quantified according to both their absolute number and as a percentage of total lymphocytes. For the purpose of analysis, the LMS (lambda, mu, sigma) method was utilized, with a 3%–97% confidence interval. Smoothing of the generated curves, was by multiple regression analysis, using the least squares method. The results of these analyses indicate distinct trends as a child ages, both in absolute numbers and in the precentage of each cell type.