The replenishment of depleted skeletal reserves of magnesium

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Abstract
Expts. with rats show that the increase of Mg in bone-ash which occurs in demineralization arises from a Ca-replacing action of Mg. This does not occur if Mg supplies are inadequate. The replenishment of skeletal Mg reserves, after depletion by acute Mg deficiency, is incomplete after a 10-day period of re-alimentation with Mg, irrespective of whether bone growth ocurs. This indicates that the re-entry of Mg into the bone salt occurs less readily than its depletion during acute deficiency.