Abstract
Mutants in the indole-3-acetic acid metabolism derived from cultured crown gall cells were tested to see whether they could utilize any one of eight indolic compounds in place of indole-3-acetic acid. Two auxin-heterotrophic mutant cell lines could not utilize indolepyruvic acid, but growth recovered when there was a supplement of indole-3-acetic acid. Indoleacetonitril and indoleacetaldoxime inhibited the growth of mutant cell lines and their parental crown gall cells. Cultured crown gall cells may have synthesized indole-3-acetic acid from tryptophan via indolepyruvic acid and indole-acetaldehyde, and also may be able to produce indole-3-acetic acid from tryptophan via tryptamine

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