Sulfadoxine resistance in the human malaria parasite Plasmodium falciparum is determined by mutations in dihydropteroate synthetase and an additional factor associated with folate utilization
Open Access
- 1 March 1997
- journal article
- research article
- Published by Wiley in Molecular Microbiology
- Vol. 23 (5) , 979-986
- https://doi.org/10.1046/j.1365-2958.1997.2821646.x
Abstract
Sulfadoxine/pyrimethamine (Fansidar) is widely used in Africa for treating chloroquine-resistant falciparum malaria. To clarify how parasite resistance to this combination arises, various lines of Pl...Keywords
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