Abstract
1. Accuracy and precision of the ferrohemoglobin solubility test, a modification of the Itano procedure, have been discussed. 2. Excellent reproducibility was achieved using 10 buffers and 10 samples with a wide range of solubilities. 3. Ranges for normal adult hemoglobin, hemoglobins A and S, S in the presence of a small amount of fetal hemoglobin, S and C, and A and C are given, together with single values for hemoglobins A and D, A and I, A and L, and A and J.

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