Changes in the Amphibian Antibody Repertoire are Correlated With Metamorphosis and not With Age or Size
Open Access
- 1 January 1992
- journal article
- research article
- Published by Hindawi Limited in Developmental Immunology
- Vol. 2 (1) , 1-6
- https://doi.org/10.1155/1992/28568
Abstract
Tadpole and adult Xenopus, manipulated to be of comparable size, exhibited stagespecific antibody expression. The production of adult-type higher-affinity anti-DNP antibodies proved to be independent of the age and size of the individual and is concomitant with the completion of metamorphosis. The appearance of new antibody specificities at such a time suggests that their expression occurs with the cell turnover and renewal during a period of morphological changes.Keywords
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