A Note on the Action of Glutamine on Cortical Spreading Depression
- 1 September 1991
- journal article
- research article
- Published by SAGE Publications in Cephalalgia
- Vol. 11 (4) , 201-204
- https://doi.org/10.1046/j.1468-2982.1991.1104201.x
Abstract
Application of a solution of 1-glutamine, 75 mM, to the pia-arachnoid surface of the dorsolateral neocortex of rabbits under dial-urethane anaesthesia was found to reversibly render the tissue insusceptible to spreading depression. It is suggested that this amide may play a part in the opposition normally offered by the tissue to undergo spreading depression. Some evidence is adduced which seems to support this suggestion.Keywords
This publication has 10 references indexed in Scilit:
- Neuroexcitatory plasma amino acids are elevated in migraineNeurology, 1990
- Magnetic field associated with spreading depression: a model for the detection of migraineBrain Research, 1988
- Glutamine Protects Neuronal Function Against Hypoxia in vitroPublished by Springer Nature ,1988
- Glutamine Synthetase: Glial Localization in BrainScience, 1977
- On the relation of glutamic acid and some allied compounds to cortical spreading depressionBrain Research, 1972
- Behavioral, unit and slow potential changes in methionine sulfoximine seizuresElectroencephalography and Clinical Neurophysiology, 1965
- Analogues of Glutamic and γ-Amino-n-butyric acids having Potent Actions on Mammalian NeuronesNature, 1961
- COMPOUNDS IN BRAIN EXTRACTS CAUSING SPREADING DEPRESSION OF CEREBRAL CORTICAL ACTIVITY AND CONTRACTION OF CRUSTACEAN MUSCLEJournal of Neurochemistry, 1959
- STRUCTURE‐ACTIVITY DETERMINANTS OF PHARMACOLOGICAL EFFECTS OF AMINO ACIDS AND RELATED COMPOUNDS ON CENTRAL SYNAPSESJournal of Neurochemistry, 1959
- INTERCORTICAL CONNECTIONS OF CORPUS CALLOSUM AS INDICATED BY EVOKED POTENTIALSJournal of Neurophysiology, 1940