THE INTAKE OF WATER BY FROGS DURING THEIR REACTION TO PITUITRIN

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Abstract
By a process of elimination, the uptake of water by frogs (R. pipiens) immersed in water and injected with pituitrin was due to entrance of water via the skin and gastrointestinal tract, no appreciable amts. entering by way of the nostrils, buccal mucosa, lungs or cloaca. Since pituitrin causes a retention of normal body water and of water entering the body by way of the gastrointestinal tract, the skin, or by injection, the essential action of pituitrin in frogs and in the doses used is to cause a retention of water rather than a stimulation of water uptake through the skin.

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